A major focus of the Medicinal Chemistry Collaborative is “natural products,” the molecules synthesized by plants, fungi, and other natural organisms. To find important examples of how natural products have contributed to medicine, one need look no further than penicillin, a molecule produced by a fungus, that sparked the antibiotic revolution. The applications of our natural products research include discovering new lead compounds for drug development, evaluating the safety and efficacy of traditional herbal medicines, and understanding the role that chemical compounds play in communication between living systems.
Fungal libraries unlike any in the world
Expanding natural products diversity to support drug discovery Under the leadership of natural products chemist Dr. Nicholas Oberlies and mycologist […]
From lowly fungus to promising therapeutic for drug resistant bacterial infections
Several drug leads isolated from our fungal library and that at Mycosynthetix are showing promising activity in vivo. One of […]
Center of Excellence for Natural Product Drug-Interaction (NaPDI) Research
Clinical studies to understand how dietary supplements alter drug metabolism The Center of Excellence for Drug Interaction Research (NaPDI) provides […]